2009-2013 Ph.D. Degree: Genetics. Departament de Genètica. Fac. Biologia. Universitat de Barcelona. Barcelona, Spain. Ph.D advisor: Dr. Marc Valls.
2008-2009 M.Sc. Degree: Developmental Biology and Genetics. Departament de Genètica. Fac. Biologia. Universitat de Barcelona. Barcelona, Spain.
2003-2008 B.Sc. Degree: Biochemistry. Faculdade de Ciências e Tecnologia. Universidade de Coimbra. Coimbra, Portugal.
My current interests are focused on understanding how evolutionary diverse plant pathogens evolved independent effector proteins to interact with a limited set of host proteins. For that our group takes advantage of the effector convergence of naturally-occurring pathogens of Arabidopsis, namely, P. syringae (Eubacteria), H. arabidopsidis (Stramenopiles) and G. orontii (Ascomycete), onto a family of plant-specific transcription factors known as TCP [1,2]. These transcription factors are known for their roles in plant development, but a growing body of evidences suggest their contribution in immune processes [2,3,4].
Besides, I am interested in understanding how rapidly plants are overcoming the selective pressure imposed by contemporary pathogens. For that, I am focusing on a pair of divergently transcribed resistance genes present in some Arabidopsis ecotypes and Brassicaceae species. I take advantage of in silico methods to infer allele prevalence, diversity and expression, based on publicly available genomic and transcriptomic datasets. I am also applying molecular biology, biochemistry and plant pathology techniques to characterize the function and the activation mechanism of these genes. This work is part of a collaboration between Prof. Jeff Dangl and Prof. Jonathan Jones.
Nishimura MT*, Monteiro F*, Dangl JL. Treasure your exceptions: unusual domains in immune receptors reveal host virulence targets. Cell 161(5):957-60 (2015). doi: 10.1016/j.cell.2015.05.017. PMID: 26000473
Höckner M, Stefanon K, de Vaufleury A, Monteiro F, Pérez-Rafael S, Palacios O, Capdevila M, Atrian S, Dallinger R. Physiological relevance and contribution to metal balance of specific and non-specific Metallothionein isoforms in the garden snail, Cantareus aspersus. Biometals 24, 1079-1092 (2011). doi:10.1007/s10534-011-9466-x. PMID: 21625890
Orihuela R, Monteiro F, Pagani A, Capdevila M & Atrian S. Evidence of Native Metal–S2−Metallothionein Complexes Confirmed by the Analysis of Cup1 Divalent-Metal-Ion Binding Properties. Chem. Eur. J. 16, 12363-12372 (2010). doi: 10.1002/chem.201001125. PMID: 20839184
* - Co-first authors