Farid El Kasmi
Education:
2004 Diploma
(Master’s Degree) in Biology (with highest grades) at the Eberhard Karls
University of Tuebingen, Germany
2011 PhD
in Biology (Cell Biology – magna cum laude) at the Eberhard Karls University of
Tuebingen, Germany
Project description:
I am interested in elucidating the molecular mechanisms regulating intracellular plant immune receptor activation and signaling. The projects I am working on deal with the characterization of RPM1 activation by the small plasma membrane protein RIN4, the regulation of RPM1 protein turn-over and the role of RPM1 in the regulation of the hypersensitive response in Arabidopsis thaliana.
Publications:
Wang GF, Ji J, El
Kasmi F, Dangl L. J, Johal G, Balint-Kurti P. Molecular and Functional
Analyses of a Maize Autoactive NB-LRR Protein Identify Precise Structural
Requirements for Activity. PLoS Pathog. 2015; 11(2): e1004674.
Munch D, The OK, Gro
Malinovsky F, Liu Q, Vetukuri RR, El Kasmi F, Brodersen P,
Hara-Nishimura I, Dangl JL, Petersen M, Mundy J and Hofius D. Retromer
Contributes to Immunity Associated Cell Death in Arabidopsis. Plant Cell 2015;
27 (2): 463-79.
Jürgens G, Park M,
Richter S, Touihri S, Krause C, El Kasmi F and Mayer U. Plant
Cytokinesis: a tale of membrane traffic and fusion. Biochem. Soc. Trans. 2015;
43 (1): 73-78.
Chung E, El Kasmi
F, He Y, Loehr A, Dangl JL. A Plant Phosphoswitch Platform Repeatedly
Targeted by Type III Effector Proteins Regulates the Output of Both Tiers of
Plant Immune Receptors. Cell Host and Microbe 2014 Oct
8;16(4):484-94.
El Kasmi
F, Stierhof Y.-D,
Mayer U, Laura Conner, Lingtian Kong, Anton A. Sanderfoot, and Juergens G.
SNARE complexes of different composition jointly mediate membrane fusion in
Arabidopsis Cytokinesis. Molecular Biology of the Cell. 2013 May;
24 (10): 1593-601.
Reichardt I, Slane
D, El Kasmi F, Knöll C, Fuchs R, Mayer U, Mueller I, Lipka V,
Jürgens G. Mechanisms of functional specificity among plasma-membrane syntaxins
in Arabidopsis. Traffic. 2011 Sep; 12 (9): 1269-80.
El Kasmi
F, Pacher T, Strompen G, Stierhof Y.-D,
Bednarek SY, Rio G, Koncz G, Juergens G. Arabidopsis SNARE protein SEC22
is essential for gametophyte development and maintenance of Golgi-stack
integrity. Plant J. 2011 Apr; 66 (2): 268-79.
Stierhof Y.-D and El
Kasmi F. Strategies to improve the antigenicity, ultrastructure
preservation and visibility of trafficking compartments in Arabidopsis tissue. Eur
J Cell Biol. 2010 Feb-Mar; 89 (2-3): 285-97.
Kwon C, Neu C,
Pajonk S, Yun HS, Lipka U, Humphry M, Bau S, Straus M, Kwaaitaal M, Rampelt H, El
Kasmi F, Juergens G, Parker J, Panstruga R, Lipka V, Schulze-Lefert P.
Co-option of a default secretory pathway for plant immune responses. Nature.
2008 Feb 14; 451 (7180): 835-840.
Strompen G, El
Kasmi F, Richter S, Lukowitz W, Assaad FF, Juergens G, Mayer U. The
Arabidopsis HINKEL gene encodes a kinesin-related protein involved in
cytokinesis and is expressed in a cell cycle-dependent manner. Curr Biol.
2002 Jan 22; 12 (2): 153-158.