Nak Hyun Kim

Email Nak Hyun


 
Education:

2013                   PhD in Bioscience and Technology, Korea University, South Korea

2006                   BS in Bioscience and Technology, Korea University, South Korea

 Project Description:

I am interested in understanding the activation mechanism of plant nucleotide-binding and leucine rich repeat (NLR, resistance) proteins.

My current project involves the engineering of rice NLR protein complex RGA4 and RGA5a,
with the goal of expansion of pathogen effector recognition specificity of RGA5a.  

 List of Publications:

1. Lee, S. C., Kim, D. S., Kim, N. H. and Hwang, B. K. 2007. Functional analysis of the promoter of the pepper pathogen-induced gene, CAPIP2, during bacterial infection and abiotic stresses. Plant Science 172(2): 236-245.

2. Choi, H. W., Lee, B. G., Kim, N. H., Park, Y., Lim, C. W., Song, H. K., and Hwang, B. K. 2008. A role for a menthone reductase in resistance against microbial pathogens in plants. Plant Physiology 148(1): 383-401.

3. Hong, J. K., Choi, H. W., Hwang, I. S., Kim, D. S., Kim, N. H., Choi, D. S., Kim, Y. J. and Hwang, B. K. 2008. Function of a novel GDSL-type pepper lipase gene, CaGLIP1, in disease susceptibility and abiotic stress tolerance. Planta 227(3): 539-558.

4. Choi, H. W., Choi, Y. J., Kim, D. S., Hwang, I. S., Choi, D. S., Kim, N. H., Lee, D. H., Shin, H. D., Nam, J. S. and Hwang, B. K. 2009. First Report of powdery mildew caused by Erysiphe cruciferarum on Arabidopsis thaliana in Korea. The Plant Pathology Journal 25(1): 86-90.

5. Kim, N. H., Choi H. W., and Hwang, B. K. 2010. Xanthomonas campestris pv. vesicatoria effector AvrBsT induces cell death in pepper, but suppresses defense responses in tomato. Molecular Plant-Microbe Interactions 23 (8): 1069-1082.

6. Hwang I. S., Kim, N. H., Choi D. S., and Hwang, B. K. 2012. Overexpression of Xanthomonas campestris pv. vesicatoria effector AvrBsT in Arabidopsis triggers plant cell death, disease and defense responses. Planta 236(4): 1191-1204.

7. Choi, H. W., Kim, D. S., Kim, N. H., Jung, H. W., Ham, J. H., and Hwang, B. K. 2013. Xanthomonas filamentous hemagglutinin-like protein Fha1 interacts with pepper hypersensitive induced reaction protein CaHIR1 and functions as a virulence factor in host plants. Molecular Plant-Microbe Interactions 26: 1441-1454.

8. Choi, H. W., Kim, N. H., Lee, Y. K., and Hwang, B. K. 2013. The pepper extracellular xyloglucan-specific endo-β-1,4-glucanase inhibitor protein gene, CaXEGIP1, is required for plant cell death and defenses. Plant Physiology 161: 384-396.

9. Kim, N. H., Kim, B. S., and Hwang B. K. 2013. Pepper arginine decarboxylase is required for polyamine and γ-aminobutyric acid signaling in cell death and defense responses. Plant Physiology 162: 2067-2083.

10. Kim, N. H., Kim, D. S., Chung, E. H., and Hwang, B. K. 2014. Pepper suppressor of the G2 allele of skp1 interacts with the receptor-like cytoplasmic kinase1 and type III effector AvrBsT and promotes the hypersensitive cell death response in a phosphorylation-dependent manner. Plant Physiology 165: 76-91.

11. Hwang, I. S., Choi, D. S., Kim, N. H., Kim, D. S., and Hwang, B. K. 2014. The pepper cysteine/histidine-rich DC1 domain protein CaDC1 binds both RNA and DNA and is required for plant cell death and defense response. New Phytologist 201: 518-530.

12. Hwang, I. S., Choi, D. S., Kim, N. H., Kim, D. S., and Hwang, B. K. 2014. Pathogenesis-related protein 4b interacts with leucine-rich repeat protein 1 to suppress PR4b-triggered cell death and defense response in pepper. Plant Journal 77: 521-533.

13. Kim, D. S., Kim, N. H., and Hwang, B. K. 2015. GLYCINE-RICH RNA-BINDING PROTEIN1 interacts with RECEPTOR-LIKE CYTOPLASMIC PROTEIN KINASE1 and suppresses cell death and defense responses in pepper (Capsicum annuum). New Phytologist 205: 786-800.

14. Kim, D. S., Kim, N. H., and Hwang, B. K. 2015. The Capsicum annuum class IV chitinase ChitIV interacts with receptor-like cytoplasmic protein kinase PIK1 to accelerate PIK1-triggered cell death and defence. Journal of experimental botany 66 (7), 1987-1999.

15. Choi, D. S., Kim, N. H., and Hwang, B. K. 2015. The pepper phosphoenolpyruvate carboxykinase CaPEPCK1 is involved in plant immunity against bacterial and oomycete pathogens. Plant molecular biology 89 (1-2), 99-111.

16. Choi, D. S., Kim, N. H., and Hwang, B. K. 2015. Pepper mitochondrial FORMATE DEHYDROGENASE1 regulates cell death and defense responses against bacterial pathogens. Plant physiology 166 (3), 1298-1311.

17. Kim, N. H., Lee, D. H., Choi, D. S., and Hwang, B. K. 2015. The pepper GNA-related lectin and PAN domain protein gene, CaGLP1, is required for plant cell death and defense signaling during bacterial infection. Plant Science 241, 307-315.

18. Kim, N. H., and Hwang, B. K. 2015. Pepper aldehyde dehydrogenase CaALDH1 interacts with Xanthomonas effector AvrBsT and promotes effector-triggered cell death and defence responses. Journal of experimental botany 66 (11), 3367-3380.

19. Kim, N. H., and Hwang, B. K. 2015. Pepper pathogenesis-related protein 4c is a plasma membrane-localized cysteine protease inhibitor that is required for plant cell death and defense signaling. The plant journal 81 (1), 81-94.

20. Kim, N. H., and Hwang, B. K. 2015. Pepper heat shock protein 70a interacts with the type III effector AvrBsT and triggers plant cell death and immunity. Plant physiology 167 (2), 307-322.